Services and expertise
- Informations: interactions (yes or no answer), affinity, binding kinetics, thermodynamics (5°C to 40°C), stoichiometry and active concentrations.
- Samples: proteins, nucleic acids, small molecules (>180 Da or > 100 Da), liposomes, bacteria, extracts.
- Recovery function: the instrument can recover compounds bound to the functionnalized surface.
- Sensorchips are available for the immobilisation of compounds via thiol, amines, aldehyde functions, for streptavidin/biotin coupling, Tag-HIS and liposomes capturing.
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Measured parameters: association rates 103 to 107 M-1s-1, dissociation rates : 5 10-6 to 10-1s-1, equilibrium constant 104 to 2.1010 M-1, concentration: 10-3 to 10-11 M.
Equipment
- BIAcoreTM 3000
- BIAcoreTM T200
www.biacore.com
Access
Main contact
Scientific expert: Carmelo Di Primo
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Technical manager: Laetitia Minder
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